Bank Of Question Of Pharmacology And Therapeutic | Pharmacy Level 5

1.  What are receptors?

2.  What are the four types of receptors?

3.  What is desentization of receptors?

4.  What are the factors affecting renal elimination?

5.  What is the clinical application of elimination half-life?

6.  What is the importance of acidifying or alkanizing urine?

 

7.  What are organs involved in metabolism?

8.  What are the factors affecting metabolism of drugs?

9.  List enzymes involved in phase 1 metabolism od drugs

10.     How can first pass effect be avoided?

11.     What is the meaning of Volume of distribution?

12.     What are factors affecting drug distribution?

13.     What is the clinical application of Volume of distribution?

14.     List drugs with a large volume of distribution

15.     What is the relationship between volume of distribution and elimination?

 

16.     What is absorption?

17.     What are the factors affecting absorption of drugs?

18.     What is absolute bioavailability?

19.     Whay is the clinical use of bioavailability

20.     What is absorption?

21.     What are the factors affecting absorption of drugs?

22.     What is absolute bioavailability?

23.     Whay is the clinical use of bioavailability

24.     What are the indications of acyclovir cream?

25.     What is the mechanism of action of topical antifungals?

26.     What is the mechanism of terbinafine hydrochloride?

27.     What are the adverse effects of acetyl salicylic acid?

28.     What are the indications for Gold compounds?

29.     What do you understand by the term REYES syndrome?

 

30.     What are the groups of drugs used in management of asthma?

31.     What are contraindications of drugs for asthma?

32.     What is the mechanism of action of codein (antitussive)?

33.     What is the mechanism of action of insulin?

34.     What are adverse effects of Sulphonylureas?

35.     Why is not advised to combine MAOIs and sulphonyl urea?

36.     Which drugs are known to be enzyme inducers?

37.     What is the importance of enzyme inhibition?

38.     What is the consequence of enzyme induction on a pro drug?

39.     What is partial agonist?

40.     What is physiological antagonism?

41.     What are the factors which affect drug responses among individuals?

42.     Why do first generation antipsychotics produce extra pyramidal symptoms?

43.     What are advantages of second generation compared to the first generation antipsychotics?

44.     What are contraindications of phenothiazines?

45.     What is the mechanism of action of benzodiazepines in controlling anxiety

46.     What are adverse effects of benzodiazepines?

47.     What is the mechanism of action of Buspirone

48.     What is the mechanism of action of phenytoin?

49.     Anticonvulsants are contraindicated in which conditions?

50.     Which drugs should be avoided to be co-administered with carbamazepine ?

51.     What are approaches in management of poisoned patients?

52.     What are antidotes for ethanol poisoning?

53.     What is the treatment for isoniazid poisoning?

54.     What is a toxicant?

55.     What are branches of toxicology?

56.     What are mechanisms by chemicals/drugs produce toxicity?

57.     What is the mechanism of action of Zidovudine?

58.     What are adverse effects of efavirenz?

59.     Why do NRTIs cause lactic acidosis?

60.     Mention drugs used in treatment of amoebiasis

61.     What is the mechanism of action for metronidazole?

62.     How does bacterial resistance to metronidazole develop?

63.     What is the mechanism of action of aminoglycosides?

64.     What are contraindications of aminoglycosides?

65.     How does bacterial resistance to aminoglycosides develop?

66.     What is the mechanism of action of fluoroquinolones?

67.     What are contraindications of ciprofloxacin?

68.     What are the side effects of  gatifloxacin?

69.     What is the mechanism of action of macrolides?

70.     How does resistance to macrolides develop?

71.     What are drug interactions associated with erythromycin?

72.     What are adverse effects of penicillins?

73.     What is the mechanism of action of cephalosporins?

74.     What contraindications of penicillins?

75.     What are the common adverse effects of ketoconazole?

76.     What is the mechanism of action of Echinocandins?

77.     What are advantages of using fluconazole versus fluconazole in systemic conditions?

78.     What are the  contraindications of primaquine

79.     What is the mechanism of action of quinine?

80.     What are adverse effects of quinine?

81.     What are contraindications of antihelminthics?

82.     What is the mechanism of action of Ivermectin

83.     What are adverse effects of antihelminthics?

84.     What are the indication of Metronidazole and Tinidazole

85.     What is the dose of Metronidazole

86.     Which adult dose Tinidazole

87.     What is the common adverse effect of Metronidazole and Tinidazole

88.     What are the indications of vitamin B6?

89.     What are symptoms/signs associated with hypervitaminosis?

90.     How does vitamin K produce its pharmacological effects?

91.     What are the other forms of vitamin D?

92.     What are indications of immunosuppressants?

93.     What are the general side effects of immunosuppressants?

94.     What are the contraindications of immunosuppressants

95.     What are the indications of cyclophosphamide?

96.     What are the general/common adverse effects of anticancer drugs?

97.     How do Vinca alkaloids produce their pharmacological effects?

98.     What are local Anaesthetics?

99.     What is the mechanism of action of local anaesthetics?

100.   What are the side effects of local anaesthetics?

101.   What are contraindications of local anaesthetics?

102.   What are General Anaesthetics?

103.   What is the mechanism of action of general anaesthetics?

104.   What are the side effects of general anaesthetics?

105.   What are contraindications of general anaesthetics?

 

106.   What are the mechanisms of antiarrhythmic drugs?

107.   What are the drug interactions of action of amiodarone?

108.   What are the side effects of proicanamide?

109.   What are contraindications of quinidine?

110.   What are the adverse effects of ASA?

111.   What is the mechanism of  action of clopidogrel?

112.   What are contraindications of antiplatelet Drugs? What are the contraindications of Beta blockers

113.   What are the adverse effects of calcium channel blockers?

114.   What are drug interactions associated with beta blockers?

115.   What are the adverse effects of Heparins?

116.   What is the mechanism of action of UFH?

117.   What are contraindications of warfarin?

118.   What are the adverse effects of digoxin?

119.   How is digoxin toxicity treated/ controlled?

120.   What is the mechanism of action of digoxin?

121.   What are the contraindications of TCAs?

122.   What are side effects of MAOIs?

123.   Why are MAOIs not preferred in patients consuming tyramine containing foods?What are the main catecholamines deficient in depression?

124.   What is the mechanism of action of levodopa?

125.   What are contraindications of Entacapone?

126.   What are adverse effects of bromocriptine?