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PHARMACOLOGY BANK OF QUESTIONS | CMT NTA LEVEL 5 | DOWNLOAD

 PHARMACOLOGY BANK OF QUESTIONS | CMT NTA LEVEL 5 | DOWNLOAD

1.  Pharmacologic therapies for congestive heart failure include

A. The removal of retained salt and water with vasodilators   

B. Direct treatment of the depressed heart with positive inotropic drugs  

C. Reduction of preload by angiotensin-converting enzyme inhibitors.   

D. Reduction of afterload by venous dilators

E. Beta-adrenoceptor blockers late stage can be used

  

2. Facts about Angiotensin Converting Enzyme (ACE) Inhibitors  

A. The ACE inhibitors such as captopril increased peripheral resistance and thereby increased afterload,  

B. They also retain salt and water  (by increasing aldosterone secretion).

C. Increase the long-term remodelling of the heart and vessels  

D. Side effects include cough, loss of taste, rash, abdominal pain, angioedema,

E. Its has no effect on sympathetic activity.

 

DOWNLOAD HERE PHARMACOLOGY BANK OF QUESTIONS | CMT NTA LEVEL 5

 

3. Poly-resistant TB drugs means

A. Resistance to a single ant TB drug  

B. Resistance to at least isoniazid and rifampicin    

C. Resistance to more than one drug, but not the combination of isoniazid and rifampicin

D. Resistance to any flouroquinolone , and at least one of the three second line injectable drugs  

E. Resistance to Rifampicin detected using phenotypic or genotypic methods

 

4.  Regarding pharmacokinetics of Paracetamol (Acetaminophen)  

A. Indicated for moderate to severe  pain and pyrexia

B. Syrups, injectable and suppositories preparations are also available

C. Reye's syndrome its side effect

D. Contraindicated to patient with Peptic ulceration or gastritis and bleeding disorders like haemophilia  

E. Given with cautions for a patient with  Hepatic impairment , Renal impairment

5.  About effect of Opioid Analgesics:

A. They provide relief of moderate to severe pain

B. They act on the peripheral nervous  system by impairing the perception of both visceral and somatic pain   

C. Rare cause sedation and respiratory depression on high dose

D. Are restricted to cross the blood brain barrier  

E. Adverse Effects can cause diarrhea

 

 

6. Factors are thought to interfere with the mucosa protective mechanisms and

    associated with increased incidence of peptic ulcer

A. Use of non-steroidal anti inflammatory drug (NSAIDs)   

B. Frequently eating  habits  

C. Food poisoning

D. hypertension

E. Presence of bacteria called Helicobacter jejun in the stomach   

 

7. About Stages of Anesthesia,

A. Stage 3: Stage of Analgesia or the Stage of Disorientation

B. Stage 2: Stage of Excitement or the Stage of Delirium  

C. Stage 1: Stage of Surgical Anesthesia  

D. Stage 3: Stage of Respiratory Failure

E. Stage 4: Stage of Excitement or the Stage of Delirium  

 

8. Regarding Salbutamol

                      A. Is used in asthma and other conditions associated with reversible airway

                           obstruction

                      B. Its a beta2 antagonist

                      C. Peak plasma concentration being achieved in about 12 hours

                      D. Its action causing constriction of smooth muscles of the bronchi

                      E.  side-effects include tachycardia, peripheral vasodilation

 

9. Regarding Phenobarbitone

A. Mechanism of action is by competitive inhibitor to the effect of Gamma Amino Butyric Acid (GABA).   

B. Its  pharmacokinetcs is completely metabolize in the liver

C. Therapeutic indications, It is used for temporal lobe epilepsy, tonic clonic seizures, status epilepticus and prevention of febrile convulsions status epilepsy  

D. Drug interactions  is uncommonly   

E. Unwanted effects include insomnia and hallucination

 

10. About Chlorpromazine 

A. Often known as a ‘major tranquillizer

B. D2 dopamine receptors agonist

C. Therapeutic uses o Chlorpromazine is used in the treatment of  status epilepticus

D. Adverse effects include jaundice, hypertension, and euphoria.

E. Used  to manage Parkinson’s disease patient

 

 

TRUE/FALSE QUESTIONS

1. Principles of TB Treatment - The Cornerstones of TB Control , include

A. …………. Early case finding

B.  ………… Adequate treatment for 4months duration

C.  …………. Appropriate combination of different drugs with the right dosage

D. …………. Direct observed treatment (DOT) strategy

E.  .…………. Early case finding and isolation.

 

 

2 About Initial (Intensive) Phase on TB Treatment Regimens  :

A…………. That includes the use of at least  two drugs

         B…………. There is rapid killing of the TB bacilli

         C…………. Patients mostly become non-infectious in about 2 weeks

         D…………. Streptomycin is commonly used in the initial phase

         E…………. The treatment of choice for the initial phase is the daily use of kanamycin

 

3. Fact about Antiemetic Drugs

A. …………. Vomiting is the result of activation of the vomiting centre in the brain

                               stem.    .

B. …………. Antiemetics should only be prescribed when the cause of vomiting is

                               known.

C. …………. Nausea and vomiting are common in the first trimester of pregnancy and

                               require drug therapy.   

D. ………….  Promethazine is an antihistamine which acts on the H1 receptors in the

                              vomiting centre

E. …………. Adverse effects include weight gain.

4. Facts about Ketamine

A. …………. A short acting local anaesthetic with analgesic properties

B. …………. Normally administered I.V or I.M, it quickly crosses the blood-brain

                               barrier.

C. …………. Adverse effects include hepatitis and blurred vision

D. …………. Contraindications in Raised intracranial pressure

E. …………. Its among of Opioid Analgesics drugs

 

 

 

MATCHING QUESTIONS                   (10 )

Question 1.

Column A DRUGS

Column B MODE OF ACTION

1.  ……... Lignocaine  

A. The antagonist of opioid , used in suspected opioid overdose

2. ……… Isoniazid

B. positive inotropic drug

3. ………Naloxone

C.  Angiotensin Converting Enzyme (ACE) Inhibitors

4. .……… captopril

D. They act at benzodiazepine receptors which are associated with gamma-amino butyric acid (GABA) receptor.

5. .……… Digoxin

E. Local anaesthesia act by preventing transmission of impulses along nerve fibres and its nerve endings

 

F. Reduces the inflammatory component in chronic asthma

 

G. Bacteriostatic against actively growing TB bacilli Inhibits the synthesis of one or more metabolites.

 

H. Inhibits the synthesis of mycolic acid in the  

       mycobacterial cell wall .

 

Question 2.

Column A: Anatomical terminologies

Column B: Definition

1.  ……. Receptor

A. A drug that binds to a receptor and elicits an effect.

2. ……...Agonist

 

B. A measure of the dose that is required to produce a response.

3. …...…Antagonist

C. Chemotherapeutic

4..……… Toxic dose (TD

D. A specialized target macromolecule present on cell surface or intracellular.

5..……… Effective dose (ED50)

E. drug that binds to a receptor and does not elicit an effect

 

F. how much drug is required to elicit an unwanted adverse effect..

 

G. The ability of a drug to be more toxic to the invader than to the host

 

H. When two antibiotics agents with the same mechanisms of action are used.

 

SHORT ANSWER QUESTIONS

1. Mentions five Aims of Anti-TB Treatment                                                      ( 5 )

i. …….

ii. …….

iii. …….

iv. …….

v. …….

 

2. A) Mention two factors that protect the gastric mucosa membrane.                                                    

i. ………..

ii. ………..

 

   B) Drugs for peptic ulcers are classified into three groups, mention them                                                         

i. ……..

ii. ……..

iii. ……..

 

3. Mention FIVE (5) Risk Factors for Ant TB Drug Resistance                                

i. ……..

ii. …….

iii. ……..

iv. ……….

v. ………..

 

4. Mention FIVE (5) Groups of Medicines Acting on the CNS.                                                                  

i. ………….

ii. ………….

iii. ………….

iv. …………

v. …………..

 

 

 5.   Anti-asthmatic drugs are mainly categorized into two major groups,  

a) Mention them                                                                            (2)        

i. ………………….

ii. ………………….

b) Give an example for each   group mentioned above               (2 )

iii. ………………….

iv. ………………….

c) Mention the mechanism of action ( 1 )

v. ………………….

 

 

6.      (a)   Mention four   Anxiolytics and Hypnotics  characteristic effects                                                                                                                   ( 5 )   

i. ……..

ii. ………

iii. ………

iv. ………

       (b) Give one example of Anxiolytic drug                                                      (1)

i. ……

 

7. (a) Mention four contraindications of Opioid uses                                           ( 4)

i. ………………….

ii. ………………….

iii. ………………….

iv. ………………….

     (b) Mention one example of Opiod drug                                                            (1 )

i. ……………….

a) Mention three Anti-Epileptic Agents  in  Primary Level Health Facility                                                                      

                                                                                                                                 ( 3)

i. …………………

ii. …………………

iii. …………………

 

     b) Mention two contraindications of using Diazepam                                                                                       i. …………………

ii.  …………………

 

 

 GUIDED ESSAY QUESTIONS

1. What are the therapeutic use, adverse effects, indications and contraindications of drugs used in anaphylaxis?.     (15 )

2. Describe Tuberculosis Treatment Categories   (15 )

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