HEMATOLOGY AND BLOOD TRANSFUSION QUESTIONS | MEDICAL LABORATORY MLT 5

MICROBIOLOGY AND IMMUNOLOGY QUESTIONS | MEDICAL LABORATORY MLT 5 

MICROBIOLOGY AND IMMUNOLOGY QUESTIONS | MEDICAL LABORATORY MLT 5

1.      What is haematological disorders ?

2.      What are the blood cells disorders associated with the shape of red blood cells ?

3.      Mention the normal range of  white  blood cells

4.      Describe criteria for suitable blood donors

5.      Describe specimen collection procedure for selection of suitable blood donors for Blood Transfusion tests

6.      Describe the method of Hb estimation in Blood Transfusion for blood donor selection

7.      Define the following terms

a)      Compatibility,

b)      Rouleaux formation,

c)      Cold agglutinin,

d)      Agglutination.

e)      Autoimmune haemolytic anaemia,

f)       Fresh packed red cells,

g)      Frozen plasma and

h)      Haemolytic disease of the newborn,

8.      Explain types and role of  immunoglobulins: igg, igm, iga, igd, ige

9.      Explain the basic immune function

10.  Define what is CD4

11.  What is the aim of performing screening test for Sickle cells ?

12.  What is the pH of the buffer solution used in Leishman stain?

13.  Explain the possible expected offspring from the mating of AO and OO couple.

14.  Explain the expected front type of red cells and reverse type of an adult with genotype BB.

15.  Explain what type(s) of ABO blood grouping should a group A recipient be compatible with.

Questions:

16.  Explain importance of carrying  out compatibility tests between recipient’s serum and donor’s red cells before blood transfusion.

17.  List the steps of performing compatibility testing.

18.  List other blood groups of clinical significance.

Answers:

19.  Importance of carrying compatibility tests:

                    i.            To detect antibodies in the recipient’s serum, that  are active against antigens in the donor’s red cells.

                   ii.            To detect mistakes in ABO and Rhesus grouping.

20.  List blood group systems of clinical significance apart from the ABO and Rhesus are:

a)      MNSs

b)      P Kell

c)      Lewis

d)      Lutheran

e)      Duffy

f)       I,

21.  Define anticoagulant, TTIs, Transfusion reaction, Adverse and give examples.

22.  Explain anticoagulant used for collection of blood transfusion

23.  Define the following terms

a)      Haemagglutination,

b)      Vitro antigen- antibody reaction,

c)      Vivo antigen – Antibody reaction

24.  Describe an example of an in vitro antigen-antibody reaction and an in vitro antibody-antigen reaction.

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